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Thursday, July 16, 2020

Science & Technology

Science & Technology

  • The permission has been granted by the
  • India is planning for the nationwide rollout of Pneumonia Conjugate Vaccine (PVC) under the

  • The vaccine is a mix of several bacteria of the pneumococci family, which are known to cause pneumonia- hence 'conjugate' is included in the name of the vaccine.
  • A conjugate vaccine is a type of vaccine which combines a weak antigen with a strong antigen as a carrier so that the immune system has a stronger response to the weak antigen.
  • It is used for active immunization against invasive disease and pneumonia caused by Streptococcus pneumoniae in infants. In an invasive disease, bacteria invade parts of the body like blood fluid, brain, and spinal cords.
  • It is administered intramuscularly, i.e. injected deep into the muscles.
  • Earlier the demands for such vaccines were provided by licensed importers since the manufacturers were all based outside India.
Clinical Trials:
  • Institute has conducted Phase I, Phase II and, Phase III clinical trials of Conjugate Vaccine in India. 
  • It has also conducted clinical trials in the Gambia (referred to as Smiling Coast, West Africa).

  • Pneumonia is an acute respiratory infection of the lungs.
  • It doesn't have one single cause - it can develop from either bacteria, viruses, or fungi in the air.
  • Children whose immune systems are premature (i.e newborns) or weakened such as undernourishment, or disease like HIV are more vulnerable to pneumonia.
  • Pneumonia is contagious and can be spread through coughing and sneezing. It can also be spread through fluids, like blood during childbirth, or from contaminated surfaces.
  • Pneumonia vaccines are a vaccine against the bacterium

Serum Institute of India Pvt. Ltd
  • Based in Pune, Maharashtra it is the
  • Vaccines manufactured by the Institute are accredited by the



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